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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCNA2 All Species: 15.06
Human Site: S5 Identified Species: 30.13
UniProt: P20248 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20248 NP_001228.1 432 48537 S5 _ _ _ M L G N S A P G P A T R
Chimpanzee Pan troglodytes XP_517420 432 48476 S5 _ _ _ M L G N S A P G P A T R
Rhesus Macaque Macaca mulatta XP_001100860 432 48504 S5 _ _ _ M L G N S A P G P A T R
Dog Lupus familis XP_540965 432 48633 S5 _ _ _ M L G S S E P G P E A R
Cat Felis silvestris
Mouse Mus musculus P51943 422 47265 R6 _ _ M P G T S R H S G R D A G
Rat Rattus norvegicus Q6AY13 421 47676 S5 _ _ _ M R R H S S K S G V A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513040 465 52108 N15 I E N L H L T N T I Q K T P K
Chicken Gallus gallus P43449 395 44062
Frog Xenopus laevis P47827 415 46651
Zebra Danio Brachydanio rerio NP_694481 428 47894 S6 _ _ M S T Q G S A V H D S D I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P14785 491 56134 N12 Q I H Q D M S N K E N P G I K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38819 450 50623 A6 _ _ M G K E N A V S R P F T R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99 91.4 N.A. 85.4 46.5 N.A. 69.2 63.4 57.6 58.7 N.A. 32.5 N.A. N.A. N.A.
Protein Similarity: 100 99.5 99.3 95.3 N.A. 90.9 60.1 N.A. 76.9 72.2 70.3 69.9 N.A. 48.8 N.A. N.A. N.A.
P-Site Identity: 100 100 100 66.6 N.A. 7.6 16.6 N.A. 0 0 0 15.3 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 75 N.A. 15.3 33.3 N.A. 26.6 0 0 23 N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 31.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 30.7 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 38.4 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 9 34 0 0 0 25 25 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 9 0 0 0 0 0 0 9 9 9 0 % D
% Glu: 0 9 0 0 0 9 0 0 9 9 0 0 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % F
% Gly: 0 0 0 9 9 34 9 0 0 0 42 9 9 0 9 % G
% His: 0 0 9 0 9 0 9 0 9 0 9 0 0 0 0 % H
% Ile: 9 9 0 0 0 0 0 0 0 9 0 0 0 9 9 % I
% Lys: 0 0 0 0 9 0 0 0 9 9 0 9 0 0 17 % K
% Leu: 0 0 0 9 34 9 0 0 0 0 0 0 0 0 9 % L
% Met: 0 0 25 42 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 34 17 0 0 9 0 0 0 0 % N
% Pro: 0 0 0 9 0 0 0 0 0 34 0 50 0 9 0 % P
% Gln: 9 0 0 9 0 9 0 0 0 0 9 0 0 0 0 % Q
% Arg: 0 0 0 0 9 9 0 9 0 0 9 9 0 0 42 % R
% Ser: 0 0 0 9 0 0 25 50 9 17 9 0 9 0 0 % S
% Thr: 0 0 0 0 9 9 9 0 9 0 0 0 9 34 0 % T
% Val: 0 0 0 0 0 0 0 0 9 9 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 67 67 42 0 0 0 0 0 0 0 0 0 0 0 0 % _